AMiNDR: A Month in Neurodegenerative Disease Research

112 - Changes to RNA, Transcription & Translation in Alzheimer's Disease: January 2021

Episode Summary

In today’s episode, Marcia brings you the latest research from Jan 2021 on changes to RNA, Transcription and Translation in the context of Alzheimer’s disease. We also talk about some really in-fashion techniques like multi-omics, deconvolution, mendelian randomization and co-localization. Tune in to learn about these techniques and more! Sections in this episode: Multiomics (2 papers) 1:10 Mendelian randomization and colocalization (3) 3:45 Gene pathway and network analysis (2) 7:21 Differential gene expression/deconvolution (2) 9:41 Methylation (2) 12:35 Post translational modifications (2) 15:19 microRNAs (3) 17:38 Miscellaneous (2) 22:53

Episode Notes

In today’s episode, Marcia brings you the latest research from Jan 2021 on changes to RNA, Transcription and Translation in the context of Alzheimer’s disease. We also talk about some really in-fashion techniques like multi-omics, deconvolution,  mendelian randomization and co-localization. Tune in to learn about these techniques and more!  

 

Sections in this episode:  

Multiomics (2 papers) 1:10  

Mendelian randomization and colocalization (3) 3:45  

Gene pathway and network analysis (2) 7:21  

Differential gene expression/deconvolution (2) 9:41  

Methylation (2) 12:35  

Post translational modifications (2) 15:19  

microRNAs (3) 17:38  

Miscellaneous (2) 22:53 

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Click here to see the list of papers covered in this episode.

To access the folder with the bibliographies for the month of January, follow this link (it will be updated as we publish episodes and process bibliographies), or click the following link below:

https://drive.google.com/drive/folders/1tKnPbfs5Uedi86weYxorCNpQqC7BfD7P?usp=sharing

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Every episode of AMiNDR is the result of a huge team effort. Today's episode was scripted and hosted by Marcia Jude, reviewed by Shruti Kochhar, and edited by Alexandra Pavel. Big thanks to Elyn Rowe, Jacques Ferreira and the rest of the sorting team for sorting all the papers published in January into themes for our episodes, to our managers Sarah Louadi and Ellen Koch for keeping everything running smoothly, and props to the whole team that works very hard behind the scenes to make all this possible. 

Our music is from "Journey of a Neurotransmitter" by musician and fellow neuroscientist Anusha Kamesh; you can find the original piece and her other music on soundcloud under Anusha Kamesh or on her YouTube channel, AKMusic.   

https://www.youtube.com/channel/UCMH7chrAdtCUZuGia16FR4w   

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If you are interested in joining the team, send us your CV by email. We are specifically looking for help with abstract summary and podcast editing. However, if you are interested in helping in other ways, don't hesitate to apply anyways.  

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*About AMiNDR: *  

Learn more about this project and the team behind it by listening to our first episode: "Welcome to AMiNDR!"