AMiNDR: A Month in Neurodegenerative Disease Research

132 - Changes to synaptic function and plasticity in Alzheimer's Disease: February 2021

Episode Summary

Want to learn more about how changes in synaptic function, structure and plasticity are implicated in neurodegenerative disease pathology? We've got you covered with this episode! Glory will guide you through 18 papers from February 2021 that explore mechanisms which underlie the synaptic dysfunction that can lead to Alzheimer's disease, ranging from the molecular level to the more global level of brain-wide connectivity. Sections in this episode: Synaptic and Axonal Function (1:59) Brain Connectivity and Neuronal Networks (4:07) Metabolites and Neurotransmitters (7:20) Synaptic Plasticity (14:29) Brain Injury (22:33)

Episode Notes

Want to learn more about how changes in synaptic function, structure and plasticity are implicated in neurodegenerative disease pathology? We've got you covered with this episode! Glory will guide you through 18 papers from February 2021 that explore mechanisms which underlie the synaptic dysfunction that can lead to Alzheimer's disease, ranging from the molecular level to the more global level of brain-wide connectivity.  

 

Sections in this episode:  

Synaptic and Axonal Function (1:59)  

Brain Connectivity and Neuronal Networks (4:07)  

Metabolites and Neurotransmitters (7:20)  

Synaptic Plasticity (14:29)  

Brain Injury (22:33)  

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To access the folder with all the bibliographies for 2021 so far, follow this link (it will be updated as we publish episodes and process bibliographies), or click the following link below:

https://drive.google.com/drive/folders/1N1zx_itPkCDNYE1yFGZzQxDDR-NiRx3p?usp=sharing

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We would like to thank our amazing team for all of the work that goes into every episode of AMiNDR. Today's episode was scripted and hosted by Glory Nasseri, reviewed by Ellen Koch, and edited by Anusha Kamesh. The bibliography was created by Satish Kumar and wordcloud was generated by Sarah Louadi using www.wordart.com. Big thanks to sorting manager Elyn Rowe and the rest of the sorting team for sorting all the papers published in January into themes for our episodes, and to our managers Sarah Louadi, Ellen Koch and Anusha Kamesh, for keeping everything running smoothly.

Our music is from "Journey of a Neurotransmitter" by musician and fellow neuroscientist Anusha Kamesh; you can find the original piece and her other music on soundcloud under Anusha Kamesh or on her YouTube channel, AKMusic.   

https://www.youtube.com/channel/UCMH7chrAdtCUZuGia16FR4w   

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If you are interested in joining the team, send us your CV by email. We are specifically looking for help with sorting abstracts by topic, abstract summaries and hosting, creating bibliographies, and promotions. However, if you are interested in helping in other ways, don't hesitate to apply anyways.  

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*About AMiNDR: *  

Learn more about this project and the team behind it by listening to our first episode: "Welcome to AMiNDR!"