AMiNDR: A Month in Neurodegenerative Disease Research

173 - APP Processing & Amyloid-Beta Aggregation in Alzheimer's Disease: May 2021

Episode Summary

Hello hello to fellow baptists, tauists and all protein aggregation enthusiasts! Sarah brings you 15 papers from the month of May on Amyloid-beta aggregation! This is the first part of a 2 episode series on understanding the role Amyoid-beta plays in Alzheimer’s disease pathology, and you will hear about APP processing and localization, then Amyloid-beta generation and aggregation. We will also throw a teaser on Amyloid-beta detection with a focus on plaques, so stay tuned if you need an update far from the screen while enjoying a walk, transiting to work, or going about your house chores. Are you ready? Sections in this episode: APP Processing, Localization, & Amyloid-beta Generation (6.25) Amyloid-beta Aggregation (14.45) Plaque Structure & Characterization (25.45)

Episode Notes

Hello hello to fellow baptists, tauists and all protein aggregation enthusiasts! Sarah brings you 15 papers from the month of May on Amyloid-beta aggregation! This is the first part of a 2 episode series on understanding the role amyoid-beta plays in Alzheimer’s disease pathology, and you will hear about APP processing and localization, then amyloid-beta generation and aggregation. We will also throw a teaser on Amyloid-beta detection with a focus on plaques, so stay tuned if you need an update far from the screen while enjoying a walk, transiting to work, or going about your house chores.

Are you ready?

 

Sections in this episode:

APP Processing, Localization, & Amyloid-beta Generation (6.25)

Amyloid-beta Aggregation (14.45)

Plaque Structure & Characterization (25.45)

 

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To access the folder with all the bibliographies for 2021 so far, follow this link (it will be updated as we publish episodes and process bibliographies), or click the following link below:

https://drive.google.com/drive/folders/1N1zx_itPkCDNYE1yFGZzQxDDR-NiRx3p?usp=sharing

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Please help us by spreading the word about AMiNDR to your friends, colleagues, and networks! Another way you can help us reach more researchers is by leaving us a review on Apple Podcasts or wherever you listen to podcasts. 

We would like to thank our amazing team for all of the work that goes into every episode of AMiNDR. Today's episode was scripted by Jacques Ferreira, reviewed, hosted, and edited by Sarah Louadi, with feedback from Elle Koch on the editing. The bibliography was created by Tarini Boparai and Sarah Louadi generated the wordcloud on www.wordart.com. 

Big thanks to the sorting team for sorting all the papers published in May into themes for our episodes: Jacques Ferreira, Elyn Rowe, Ellen Koch, Christy Yu, Nicole Corso, and Naila Kuhlmann. 

Also, props to our management team, which includes Sarah Louadi, Ellen Koch, Naila Kuhlmann, Elyn Rowe, Anusha Kamesh, and Jacques Ferreira, for keeping everything running smoothly.

Our music is from "Journey of a Neurotransmitter" by musician and fellow neuroscientist Anusha Kamesh; you can find the original piece and her other music on soundcloud under Anusha Kamesh or on her YouTube channel, AKMusic.   

https://www.youtube.com/channel/UCMH7chrAdtCUZuGia16FR4w   

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If you are interested in joining the team, send us your CV by email. We are specifically looking for help with sorting abstracts by topic, abstract summaries and hosting, creating bibliographies, and promotions. However, if you are interested in helping in other ways, don't hesitate to apply anyways.  

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*About AMiNDR: *  

Learn more about this project and the team behind it by listening to our first episode: "Welcome to AMiNDR!"