AMiNDR: A Month in Neurodegenerative Disease Research

223 - Treatments Targeting Neurotransmission in Alzheimer's Disease: September 2021

Episode Summary

18 papers published in September of 2021 await you. What do they all have in common? They explore treatments for Alzheimer's disease that all target neurotransmission. If you're interested in restoring acetylcholine balance or other treatments that also improve cognitive function in Alzheimer's disease, tune in to hear Anusha take you through the literature. Sections in this episode: Discovery and synthesis of novel cholinesterase inhibitors (3.17) Tacrine-based cholinesterase inhibitors (11.26) Modifying existing treatments (16.16) Multi-target treatments (23.00)

Episode Notes

18 papers published in September of 2021 await you. What do they all have in common? They explore treatments for Alzheimer's disease that all target neurotransmission. If you're interested in restoring acetylcholine balance or other treatments that also improve cognitive function in Alzheimer's disease, tune in to hear Anusha take you through the literature.  

Sections in this episode:  

Discovery and synthesis of novel cholinesterase inhibitors (3.17)  

Tacrine-based cholinesterase inhibitors (11.26)  

Modifying existing treatments (16.16)  

Multi-target treatments (23.00)  

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You can find the numbered bibliography for this episode by clicking here, or the link below:

https://drive.google.com/file/d/1W--JfD89cCJWVbOrdFKCiZTI6cWrO54X/view?usp=sharing

To access the folder with all the bibliographies for 2021 so far, follow this link (it will be updated as we publish episodes and process bibliographies), or click the following link below:

https://drive.google.com/drive/folders/1N1zx_itPkCDNYE1yFGZzQxDDR-NiRx3p?usp=sharing

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Our team of volunteers works tirelessly each month to bring you every episode of AMiNDR. This episode was scripted, hosted and edited by Anusha Kamesh, and reviewed by Naila Kuhlmann and Ellen Koch. The bibliography and wordcloud were created by Sarah Louadi (www.wordart.com). 

Big thanks to the sorting team for taking on the enormous task of sorting all of the Alzheimer’s Disease papers into episodes each month. For September 2021, the sorters were Jacques Ferreira, Ellen Koch, Christy Yu, Sarah Louadi, Kate Van Pelt, Nicole Corso, Eden Dubchak, Kira Tosefsky, Dana Clausen, and Elyn Rowe.

Also, props to our management team, which includes Sarah Louadi, Ellen Koch, Naila Kuhlmann, Elyn Rowe, Anusha Kamesh, Jacques Ferreira, and Shruti Kocchar for keeping everything running smoothly.

Our music is from "Journey of a Neurotransmitter" by musician and fellow neuroscientist Anusha Kamesh; you can find the original piece and her other music on soundcloud under Anusha Kamesh or on her YouTube channel, AKMusic.   

https://www.youtube.com/channel/UCMH7chrAdtCUZuGia16FR4w   

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If you are interested in joining the team, send us your CV by email. We are specifically looking for help with sorting abstracts by topic, abstract summaries and hosting, audio editing, creating bibliographies, and outreach/marketing. However, if you are interested in helping in other ways, don't hesitate to apply anyways.  

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*About AMiNDR: *  

Learn more about this project and the team behind it by listening to our first episode: "Welcome to AMiNDR!"