AMiNDR: A Month in Neurodegenerative Disease Research

228 - New Variants & Genetic Insights in Alzheimer's Disease: September 2021

Episode Summary

Join Glory to learn about the newest genetic variants and mechanisms that have been linked to Alzheimer's disease. In this episode, we'll cover protective and pathogenic AD variants in genes, potential genetic biomarkers for AD, and differential gene expression that can be observed in individuals with AD. With 19 papers from September 2021, you'll hear about some genes that will be worth following up on in the near future to advance our understanding of the disease! Sections in this episode: Genetic variants (3:11) Genetic biomarkers (13:58) Differential gene expression and mRNA (18:05) miRNA regulations (22:55) New methods (26:42) Regulatory pathways (30:00) Other (33:49)

Episode Notes

Join Glory to learn about the newest genetic variants and mechanisms that have been linked to Alzheimer's disease. In this episode, we'll cover protective and pathogenic AD variants in genes, potential genetic biomarkers for AD, and differential gene expression that can be observed in individuals with AD. With 19 papers from September 2021, you'll hear about some genes that will be worth following up on in the near future to advance our understanding of the disease!  

Sections in this episode:  

Genetic variants (3:11)  

Genetic biomarkers (13:58)  

Differential gene expression and mRNA (18:05)  

miRNA regulations (22:55)  

New methods (26:42)  

Regulatory pathways (30:00)  

Other (33:49) 

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To access the folder with all the bibliographies for 2021 so far, follow this link (it will be updated as we publish episodes and process bibliographies), or click the following link below:

https://drive.google.com/drive/folders/1N1zx_itPkCDNYE1yFGZzQxDDR-NiRx3p?usp=sharing

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Our team of volunteers works tirelessly each month to bring you every episode of AMiNDR. This episode was scripted by Marcia Jude and Glory Nasseri, hosted by Glory Nasseri, edited by Michelle Grover, and reviewed by Alexandra Pavel and Ellen Koch. The bibliography was made by Lara Onbasi and the wordcloud by Sarah Louadi (www.wordart.com). 

Big thanks to the sorting team for taking on the enormous task of sorting all of the Alzheimer’s Disease papers into episodes each month. For September 2021, the sorters were Jacques Ferreira, Ellen Koch, Christy Yu, Sarah Louadi, Kate Van Pelt, Nicole Corso, Eden Dubchak, Kira Tosefsky, Dana Clausen, and Elyn Rowe.

Also, props to our management team, which includes Sarah Louadi, Ellen Koch, Naila Kuhlmann, Elyn Rowe, Anusha Kamesh, Jacques Ferreira, and Shruti Kocchar for keeping everything running smoothly.

Our music is from "Journey of a Neurotransmitter" by musician and fellow neuroscientist Anusha Kamesh; you can find the original piece and her other music on soundcloud under Anusha Kamesh or on her YouTube channel, AKMusic.   

https://www.youtube.com/channel/UCMH7chrAdtCUZuGia16FR4w   

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If you are interested in joining the team, send us your CV by email. We are specifically looking for help with sorting abstracts by topic, abstract summaries and hosting, audio editing, creating bibliographies, and outreach/marketing. However, if you are interested in helping in other ways, don't hesitate to apply anyways.  

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*About AMiNDR: *  

Learn more about this project and the team behind it by listening to our first episode: "Welcome to AMiNDR!"