AMiNDR: A Month in Neurodegenerative Disease Research

235 - Vascular Contributions to Alzheimer's Disease: September 2021

Episode Summary

Feeling like we're beating a dead horse with the amyloid cascade hypothesis? Think there's an X-factor to Alzheimer disease that is tied to both the clinical symptoms and the plaques? Could be the vasculature! Elyn is back to take you through the 12 papers published on vascular contributions to Alzheimer disease, and hopefully get you excited about this blossoming line of research and the new treatment avenues that come with it. Sections in this episode: White Matter Hyperintensities Amyloid Transport and Clearance Mechanistic Insights from Rodent Models Treatment Avenues

Episode Notes

Feeling like we're beating a dead horse with the amyloid cascade hypothesis? Think there's an X-factor to Alzheimer disease that is tied to both the clinical symptoms and the plaques? Could be the vasculature! Elyn is back to take you through the 12 papers published on vascular contributions to Alzheimer disease, and hopefully get you excited about this blossoming line of research and the new treatment avenues that come with it. 

Sections in this episode:

White Matter Hyperintensities  

Amyloid Transport and Clearance  

Mechanistic Insights from Rodent Models                                  

Treatment Avenues          

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You can find the numbered bibliography for this episode by clicking here, or the link below:

https://drive.google.com/file/d/1PjokO3cFgLOjtRyi9yjQlckHRNKMtiEM/view?usp=sharing

To access the folder with all the bibliographies for 2021 so far, follow this link (it will be updated as we publish episodes and process bibliographies), or click the following link below:

https://drive.google.com/drive/folders/1N1zx_itPkCDNYE1yFGZzQxDDR-NiRx3p?usp=sharing

Or tweet at us: @AMiNDR_podcast  

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Our team of volunteers works tirelessly each month to bring you every episode of AMiNDR. This episode was scripted & hosted by Elyn Rowe, edited by Sarah Louadi, and reviewed by Jacques Ferreira and Anusha Kamesh. The bibliography was made by Lara Onbasi and the wordcloud by Sarah Louadi (www.wordart.com). 

Big thanks to the sorting team for taking on the enormous task of sorting all of the Alzheimer’s Disease papers into episodes each month. For September 2021, the sorters were Jacques Ferreira, Ellen Koch, Christy Yu, Sarah Louadi, Kate Van Pelt, Nicole Corso, Eden Dubchak, Kira Tosefsky, Dana Clausen, and Elyn Rowe.

Also, props to our management team, which includes Sarah Louadi, Ellen Koch, Naila Kuhlmann, Elyn Rowe, Anusha Kamesh, Jacques Ferreira, and Shruti Kochhar for keeping everything running smoothly.

Our music is from "Journey of a Neurotransmitter" by musician and fellow neuroscientist Anusha Kamesh; you can find the original piece and her other music on soundcloud under Anusha Kamesh or on her YouTube channel, AKMusic.   

https://www.youtube.com/channel/UCMH7chrAdtCUZuGia16FR4w   

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If you are interested in joining the team, send us your CV by email. We are specifically looking for help with sorting abstracts by topic, abstract summaries and hosting, audio editing, creating bibliographies, and outreach/marketing. However, if you are interested in helping in other ways, don't hesitate to apply anyways.  

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*About AMiNDR: *  

Learn more about this project and the team behind it by listening to our first episode: "Welcome to AMiNDR!"