AMiNDR: A Month in Neurodegenerative Disease Research

42 - Preclinical Testing Part 1: Alzheimer's Disease August 2020

Episode Summary

In Part 1 of the AD preclinical testing papers published in August 2020, Naila gets us started with some treatments that target the cholinergic system and synaptic function, tau phosphorylation and resulting pathology, and amyloid-beta mediated toxicity. Given these are some of the hallmarks of AD pathology, trying to prevent or reverse their effects could lead to promising therapeutic outcomes, which these papers first explore in animal models. Naila will also go over a couple miscellaneous — but equally interesting — papers, so stay tuned till the end!

Episode Notes

In Part 1 of the AD preclinical testing papers published in August 2020, Naila gets us started with some treatments that target the cholinergic system and synaptic function, tau phosphorylation and resulting pathology, and amyloid-beta mediated toxicity. Given these are some of the hallmarks of AD pathology, trying to prevent or reverse their effects could lead to promising therapeutic outcomes, which these papers first explore in animal models. Naila will also go over a couple miscellaneous — but equally interesting — papers, so stay tuned till the end! 

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Today's episode was scripted & hosted by Naila Kulhmann, edited by Sarah Louadi,  and made possible by an entire team of volunteers behind the scenes.  

Our music is from "Journey of a Neurotransmitter" by musician and fellow neuroscientist Anusha Kamesh; you can find the original piece and her other music on soundcloud under Anusha Kamesh or on her YouTube channel, AKMusic.  

 

https://www.youtube.com/channel/UCMH7chrAdtCUZuGia16FR4w  

 

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If you are interested in joining the team, send us your CV by email. We are specifically looking for help with abstract summary and podcast editing. However, if you are interested in helping in other ways, don't hesitate to apply anyways.  

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*About AMiNDR: *  

Learn more about this project and the team behind it by listening to our first episode: "Welcome to AMiNDR!"